The shooting occurred on Thursday evening at around 8.00pm in via di Roccia Cencia in the east of Rome.
The victim, a 37-year-old security guard with no criminal record named Giuliano Colella, was shot seven or eight times in the head by his car as he tried to escape from his attacker, Il Messaggero reported on Friday.
Police believe that the victim had an appointment with his killer and got out of the car to speak to them before realizing it was a death trap.
Police have not ruled out that there was more than one killer.
A friend of the victim was also present at the shooting and has now become a key witness in the investigation, according to Il Messaggero.
Police have interviewed the man’s friend and recovered the shell casings from under other parked cars in the area to reconstruct the shooting.
Police are now analyzing the CCTV footage from the area and checking the phone records of the victim.
The last shooting of this nature occurred on February 6th, according to Il Messaggero, when 22-year-old Edoardo Di Ruzza, was shot four times in the head in via Torresini, eastern Rome.