According to the site Il Sismografo, the Pope pulled in 29,000 new followers each day during his recent eight-day trip to South America, versus his already impressive average of 20,000.
Of the nine accounts in languages such as French and German, his Spanish language account is the most popular - with just over nine million followers - while the English account comes in second with around 6.5 million followers.
He also comes in for some pretty solid retweet and favourite action as the message below from Wednesday suggests.
Now is the time for a change in mindset and to stop pretending that our actions do not affect those who suffer from hunger.— Pope Francis (@Pontifex) July 15, 2015
A Vatican office member writes the tweets – usually quotes from his speeches and homilies – with the Pope's approval.
The recent rise in followers means the Pope has put even more distance between himself and Matteo Renzi, who has a mere 1.96 million people hanging on his every tweet.
Despite the increase, the Vatican's top man still has a long way to go to catch up with other world leaders like US President Barack Obama, who has over 60 million followers.
Pope Francis is also well behind American entertainer Katy Perry, who has the world's most Twitter followers, with about 72.5 million.
They tend not to tweet about the same things.
WHAT ARE THOOOOOOSEEE?!?! pic.twitter.com/dZmcSHZuH9— KATY PERRY (@katyperry) July 13, 2015