But with a little planning, you can elongate a weekend or holiday in between those that fall towards the beginning or end of the week.
Here's the full list of Italy's public holidays in 2018:
January 6th – Epiphany (Saturday)
April 2nd – Easter (Monday)
April 25th – Liberation Day (Wednesday)
May 1st – Labour Day (Tuesday)
June 2nd – Republic Day (Saturday)
August 15th – Assumption of Mary/Ferragosto (Wednesday)
November 1st – All Saints’ Day (Thursday)
December 8th – Immaculate Conception (Saturday)
December 25th – Christmas Day (Tuesday)
December 26th – Saint Stephen’s Day (Wednesday)
Regional holidays
Venice: April 25th (Wednesday), Feast of St Mark
Sardinia: April 28th (Saturday), Sardinia Day
Rome: June 29th (Friday), Feast of St Peter and St Paul
Palermo: July 15th (Sunday), Feast of St Rosalia
Naples: September 19th (Wednesday), Feast of St Gennaro
Bologna: October 4th (Thursday), Feast of St Petronius
Trieste: November 3rd (Saturday), Feast of St Giusto
Bari: December 6th (Thursday), Feast of St Nicholas
Milan: December 7th (Friday), Feast of St Ambrose