Vaccines also prevented eight million cases of Covid-19, over 500,000 hospitalisations, and more than 55,000 admissions to intensive care, the ISS said in a press release announcing the publication of its report.
The report covers the period between December 27th, 2020, when the vaccination campaign began, and January 31st of this year, using a methodology initially developed for flu vaccines.
It said 72 percent of deaths avoided from the disease were among over-80s, 19 percent in the 70-79 range, 7 percent in the 60-69 range and 3 percent under 60.
Italy has been one of the countries worst affected by the pandemic, with more than 160,000 deaths reported since February 2020, the second-highest toll in Europe after Britain.
To date, almost 90 percent of the population over the age of 12 has been fully vaccinated, as well as just over 34 percent of children aged five to eleven.
Italy on Tuesday began offering a fourth dose of an anti-Covid 19 vaccine to those deemed at highest risk from the disease, including over-80s and care home residents.