Road and rail traffic in the region has been badly hampered and parts of the Via Aurelia, an old Roman road connecting the Italian capital to the French border, have been closed because of multiple landslides.
"The situation is really critical," said Renato Briano, regional representative for the civil protection agency, as the poor weather conditions continued.
The region is often affected by bad weather.
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The main city in Liguria, the port of Genoa, was badly hit by flash floods in November 2011 that claimed six lives and devastated several neighbourhoods.