On June 15th, the trio will kick off the seven day trip in the British capital, where Michelle Obama will push her initiative to promote education for girls, an issue she has already raised on trips to Japan and Cambodia.
The group will then lead the US delegation to the Milan Expo 2015.
"The presidential delegation will tour the USA Pavilion, 'American Food 2.0: United to Feed the Planet,' and participate in activities to lift up efforts to support healthier families and communities," the White House said.
In Vicenza, the family will visit members of the military and their own families stationed in the picturesque Italian city.
From there they will travel to Venice to visit the canal-crossed Unesco world heritage site.